If you’re considering starting Mounjaro (tirzepatide) for weight loss or type 2 diabetes, one of the most common concerns is the injection itself. Does it hurt? Is it difficult to do? Don’t worry — it’s simpler than you think.
This guide will walk you through exactly how to inject Mounjaro safely and comfortably — and how to get started with full support through PPRX.
What Is Mounjaro and How Is It Taken?
Mounjaro is a once-weekly injectable medication that helps regulate blood sugar and reduce appetite. It comes in a pre-filled, single-use pen — no need to measure anything or mix solutions.
It’s designed for subcutaneous injection, meaning it goes into the fatty layer under your skin, not into muscle or vein.
Step-by-Step: How to Inject Mounjaro
- Choose Your Injection Site
- The best places are:
- Your stomach (at least 2 inches away from your belly button)
- Your thigh
- The back of your upper arm (if someone is helping you)
- The best places are:
- Prepare the Pen
- Remove the pen from the fridge and let it sit at room temperature for 30 minutes.
- Wash your hands.
- Pull off the grey base cap — the pen is now ready.
- Inject
- Place the pen flat against your skin.
- Press and hold the pen firmly — you’ll hear a click.
- Keep holding until the second click (about 10 seconds), then remove the pen.
- Dispose Safely
- Throw the pen away in a sharps container or follow local disposal guidelines.
Full guidance is also provided in every PPRX order and on our website.
Does It Hurt?
Most users report very little to no pain when injecting Mounjaro.
- The needle is hidden inside the pen and is extremely fine.
- There’s no need to press a button — the pen is automatic.
- Any discomfort is usually minimal and short-lived.
If you’re nervous, our team at PPRX is happy to walk you through the first dose and provide reassurance.
Tips to Reduce Discomfort
- Inject into a different spot each week to avoid irritation.
- Let the pen reach room temperature before injecting.
- Avoid injecting into bruised, sore, or scarred areas.
- Apply a cold pack afterward if needed.
Most people quickly become confident and find it as easy as brushing their teeth once they’ve done it a few times.
Injecting Mounjaro is simple, fast, and nearly painless — especially when using the intuitive pen design. With weekly use and proper guidance, you can focus on your results, not your fears.
Start your treatment safely, with full support from a UK-registered pharmacy at www.pprx.co.uk.

At PPRX UK, we provide:
- Genuine Mounjaro pens, sourced directly from the manufacturer (Eli Lilly)
- Dispensing via a GPhC-registered UK pharmacy
- Professional consultations with UK pharmacists
- Ongoing support, dosage guidance, and repeat supply options
Whether you’re just starting or switching from Ozempic or Wegovy, we’re here to help.

📞 Get in Touch
Visit www.pprx.co.uk or contact us directly to begin your online consultation.
We offer fast, discreet UK-wide delivery and exceptional support throughout your journey.
Mounjaro is a prescription-only medicine. This article is for informational purposes only and does not replace medical advice. Always consult a qualified healthcare provider before starting treatment. nhs