Mounjaro Dosage Guide: When to Increase Your Weekly Dose (UK 2025)

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Mounjaro

If you’re new to Mounjaro (tirzepatide), you’ve probably heard that the dose increases gradually over time.
But knowing exactly when to move up can be confusing — especially when your goal is steady, safe, and effective weight loss.

At PPRX Online Pharmacy, our pharmacists explain everything you need to know about Mounjaro dosing — from your first injection to your maintenance phase — so you can stay on track with confidence.


How Mounjaro Dosing Works

Mounjaro comes in a series of pre-filled KwikPens. Each pen contains four doses (4-week supply).
You inject once a week, on the same day each week.

The purpose of the dose escalation plan is to:

  • Help your body adapt to the medication
  • Reduce the risk of side effects like nausea
  • Achieve gradual, sustainable weight loss

Typical Mounjaro Dose Schedule

StageDose (mg)DurationPurpose
12.5 mg4 weeksStarter dose to help your body adjust
25 mg4 weeksAppetite control begins to strengthen
37.5 mg4 weeksEnhanced hunger reduction
410 mg4 weeksGreater metabolic and weight effect
512.5 mg4 weeksFor continued weight loss if tolerated
615 mgOngoingMaintenance dose for long-term results

Each stage typically lasts 4 weeks, though your prescriber may adjust this based on how well you tolerate the medicine.


When to Increase Your Mounjaro Dose

You can increase your dose every 4 weeksonly if:

  • You’ve tolerated your current dose with minimal side effects
  • You still feel hungry between meals
  • You haven’t achieved expected progress after 4–6 weeks

If you experience persistent nausea, vomiting, or fatigue — stay on your current dose longer before increasing.
Always confirm with your prescriber before moving up.


When Not to Increase the Dose

  • If you’re still experiencing moderate nausea or stomach discomfort
  • If you’ve missed an injection recently (wait until your next cycle)
  • If your appetite is already well-controlled and you’re losing steadily

Increasing too fast can worsen side effects or cause you to lose weight too quickly — which isn’t sustainable long-term.


Mounjaro Strengths and Prices (October 2025)

Each KwikPen provides four once-weekly doses — a 4-week supply.

StrengthPrice
2.5 mg£199.99
5 mg£219.99
7.5 mg£299.99
10 mg£319.99
12.5 mg£334.99
15 mg£349.99

All prices include your free consultationprivate prescription, and next-day cold-chain delivery.

➡️ Buy Mounjaro UK – PPRX Online Pharmacy
➡️ Complete Your Free Consultation


Pharmacist Advice for Safe Dosing

  • Inject on the same day each week for stable results.
  • Never double a dose if you miss one.
  • Store pens in the fridge (2°C – 8°C) and never freeze.
  • Use a new needle each time.
  • Contact your pharmacist before adjusting the dose.

FAQs

How long should I stay on each dose?
Usually four weeks, but longer if you’re still adjusting or experiencing side effects.

Can I skip the lower doses and start higher?
No — starting higher increases the risk of nausea and fatigue. Always begin with 2.5 mg.

What’s the best dose for weight loss?
Many patients reach optimal results around 10 mg – 15 mg, but it varies per person.

What if I forget an injection?
If it’s been less than 4 days since your scheduled dose, inject as soon as you remember. Otherwise, wait until your next scheduled day.


Pharmacist Review

This guide was written and verified by a GPhC-registered pharmacist following MHRA and NICE guidance for safe tirzepatide prescribing in the UK.

Start your order today at www.pprx.co.uk

Mounjaro

At PPRX UK, we provide:

  • Genuine Mounjaro pens, sourced directly from the manufacturer (Eli Lilly)
  • Dispensing via a GPhC-registered UK pharmacy
  • Professional consultations with UK pharmacists
  • Ongoing support, dosage guidance, and repeat supply options

Whether you’re just starting or switching from Ozempic or Wegovy, we’re here to help.

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📞 Get in Touch

Visit www.pprx.co.uk or contact us directly to begin your online consultation.
We offer fast, discreet UK-wide delivery and exceptional support throughout your journey.


Mounjaro is a prescription-only medicine. This article is for informational purposes only and does not replace medical advice. Always consult a qualified healthcare provider before starting treatment. nhs

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