Getting weight loss injections through PPRX
Mounjaro and Wegovy are prescription-only medicines. With us, the prescription is a private one, issued by a UK prescriber after an online consultation, and it's part of the price of the medicine.
The consultation asks about your health and takes a few minutes. A UK prescriber reviews every answer and can ask you questions or decline. If treatment is suitable, our GPhC-registered pharmacy dispenses it for next working day delivery. How it works goes through each step.
Who can get weight loss injections
Mounjaro, Wegovy and the Wegovy Pill are licensed in the UK for adults with a BMI of 30 or more, or 27 or more with at least one weight-related health condition. Our online service treats adults aged 18 to 65 with a BMI of 27 to 50.
Some people can't be treated online, including anyone who is pregnant, breastfeeding or trying to conceive, or who has had pancreatitis or an eating disorder. The eligibility guide lists the criteria in full.
The treatments a prescriber can choose from
- Mounjaro (tirzepatide): a once-weekly injection that acts on GLP-1 and GIP.
- Wegovy (semaglutide): a once-weekly injection that acts on GLP-1.
- Wegovy Pill (oral semaglutide): a once-daily tablet, with no needles and no fridge.
- Orlistat and Alli: capsules that work in the gut rather than on appetite.
Weight loss treatments at PPRX compared| Treatment | How it's taken | How it works | Average weight loss in its main trials | From |
|---|
| Mounjaro | Injection, once a week | Acts on GLP-1 and GIP to reduce appetite | 16.0% to 22.5% on 5 to 15 mg over 72 weeks, against 2.4% on placebo (SURMOUNT-1) | £194.99 per pen |
|---|
| Wegovy | Injection, once a week | Acts on GLP-1 to reduce appetite | 14.9% on 2.4 mg over 68 weeks, against 2.4% on placebo (STEP 1) | £144.99 per pen |
|---|
| Wegovy Pill | Tablet, once a day on an empty stomach | The same medicine as Wegovy, by mouth | 13.6% on 25 mg over 64 weeks, against 2.2% on placebo (OASIS 4) | £138.99 per pack |
|---|
| Orlistat | Capsule with each main meal | Stops some of the fat you eat being absorbed | About 3.2 kg more than placebo after a year (pooled trials) | £34.99 per pack |
|---|
| Alli | Capsule with each main meal | As orlistat, at half the dose, without a prescription | 4.6% over 6 months, against 2.2% on placebo (pooled trials) | £64.99 per pack |
|---|
The trial figures are averages, alongside a reduced-calorie diet and more activity, as reported in each medicine's UK product information. The trials were run separately, in different people and for different lengths of time, so they can't be set against each other directly. Which one suits you depends on your health, your history and how you get on with a medicine. That's the prescriber's decision, made with you. Our comparison of Mounjaro and Wegovy sets out the differences.
What's included
- The medicine itself
- The online consultation and the prescriber's review
- The private prescription
- Cold-chain packaging for injections, with needles, alcohol wipes and a sharps bin
- Tracked next working day UK delivery
- Messages with our pharmacists and clinicians after you start
There are no separate consultation, prescription, dispensing or delivery fees.
Delivery
Orders are delivered by Royal Mail Special Delivery the next working day after dispensing, in plain, unbranded packaging, with nothing on the outside to say what's inside or who it's from. Injections are packed cold-chain, and you get a tracking link when your order leaves the pharmacy.
What treatment costs
Each pen lasts four weeks. Wegovy is £144.99 to £289.99 per pen and Mounjaro £194.99 to £349.99 per pen, depending on the dose. The injections start on the lowest dose and step up, so the first months usually cost less than later ones.
You pay when you place an order, after your consultation. If the prescriber decides treatment isn't suitable, you are not supplied and you are refunded in full. Every price, per dose, is on our pricing and payment page.
Reviews of your progress
Mounjaro, Wegovy and the Wegovy Pill start at a low dose and step up, usually about every four weeks, until you reach the dose your prescriber agrees is right for you. Your prescriber can keep you on a lower dose if it is working.
Every order is checked by our pharmacy team, with ongoing support as your dose changes, and you can message our pharmacists whenever you have a question about your treatment. The dosing guide and side effects guide explain what to expect.
What happens when you stop
Weight tends to come back after stopping a weight-loss injection, because the medicine's effect on appetite wears off. Two trials tested this by switching some people to a placebo after a period on treatment:
- SURMOUNT-4 (Mounjaro): after 36 weeks on tirzepatide, those who carried on lost a further 6.7% of their weight over the next year on average, while those switched to placebo regained 14.8%.
- STEP 4 (Wegovy): after 20 weeks on semaglutide, those who carried on lost a further 7.9% over 48 weeks, while those switched to placebo regained 6.9%.
That doesn't mean treatment has to be forever. It means stopping is worth planning with your prescriber: when, whether to come down to a lower dose first, and the eating and activity habits that help keep the weight off. The results guide covers what the trials found in more detail.
How to spot an unregulated seller
Fake weight-loss pens are in circulation, and the MHRA says the only way to be sure you get a genuine GLP-1 medicine is from a legitimate pharmacy, after a consultation with a healthcare professional. Warning signs include:
- No prescription or consultation needed, or a tick-box form with no way to speak to a prescriber.
- Sold through social media, messaging apps or beauty salons.
- A price that seems too good to be true.
- Powder in a vial that you mix yourself, or products sold as "research peptides". Licensed GLP-1 medicines come as pre-filled pens or tablets.
- No GPhC registration number, no named pharmacy or superintendent pharmacist, or details that don't match the GPhC register.
Our GPhC registration number is 9012740, and you can check it on the GPhC register yourself. Our guide to checking an online pharmacy explains each check and how to report a seller.
Sources
- NICE TA1026: Tirzepatide for managing overweight and obesity
- NICE TA875: Semaglutide for managing overweight and obesity
- Mounjaro KwikPen Summary of Product Characteristics (emc)
- Wegovy FlexTouch Summary of Product Characteristics (emc)
- NHS: Overweight and obesity in adults, treatment
- Wegovy tablets Summary of Product Characteristics (emc)
- Xenical 120 mg Summary of Product Characteristics (emc)
- Alli 60 mg Summary of Product Characteristics (emc)
- MHRA: GLP-1 medicines for weight loss and diabetes, what you need to know (updated 5 February 2026)
- GPhC: Guidance for registered pharmacies providing pharmacy services at a distance, including on the internet (February 2025)